Emotional factors have been associated with periodontal disease since 1995.The ability of psychological stress to suppress the cellular immune response has long been known. A complex network of bidirectional signals connects the neurological, endocrine, and immune systems, allowing communication between the central nervous system and immune cells. This network's homeostasis is disrupted by stress, which changes immune function. A positive association can be seen based on the literature review. There was a link discovered between stress and periodontal disease. Assessing patients for stress is an important factor in determining periodontal disease activity and could be useful in motivating patients towards the direction of improved overall health. Individuals who face social, emotional or have financial difficulties or use a passive coping method could be at danger. It is necessary to track the stress levels of the patients being treated. Questionnaires are available that assess stress levels and coping strategies. In periodontal practice, patients have a recall mechanism to assess the stress associated at regular periodic intervals.