Zum Hauptinhalt springen Zur Suche springen Zur Hauptnavigation springen

DNA and Protein Changes in Alzheimer's Disease

Jianquan Wang
Alzheimer's disease is a progressive, irreversible, neurodegenerative disease. The key to understanding this disease is to elucidate the pathogenesis of neuron degeneration in specific brain regions. In this study, we found that there is increased DNA oxidation in patient brain compared to age-matched control subjects, especially in mitochondrial DNA, and that the changes in both nuclear and mitochondrial DNA bases will affect protein expression in mitochondria and contribute to neurodegeneration in Alzheimer's disease.
Autor: Wang, Jianquan
EAN: 9783659839832
Sprache: Englisch
Seitenzahl: 156
Produktart: kartoniert, broschiert
Verlag: Scholar's Press
Schlagworte: Protein / Eiweiß
Größe: 150 × 220