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Pyrimidine-versatile scaffold with diverse therapeutic potential

Jeelan Basha N
Pyrimidines, basically nitrogen containing heterocycles have been considered for the medicinal potential for the last few decades. This heterocycle, which also play vital role as DNA and RNA bases. Literature evidences the importance of this molecule as potent anticancer drugs. However, its toxicity and drug resistance results in a difficult challenge for the medicinal chemist to develop the novel pyrimidines with strong anticancer potential with a least toxicity and drug resistance. Still there is lot of scope on this molecule.
Autor: Basha N, Jeelan
EAN: 9786204982496
Sprache: Englisch
Seitenzahl: 52
Produktart: kartoniert, broschiert
Verlag: LAP Lambert Academic Publishing
Untertitel: 2, 4 and 5-subtituted pyrimidines. DE
Schlagworte: Pyrimidine DNA Base anticancer Antiviral Medicinal Drugs
Größe: 150 × 220