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Gene Regulation of Gene Expression in Human Genome

Nebras Rada Mohammed
Gene Sequence of DNA or RNA which codes for molecule that has function. Product include: SiRNA, rRNA, miRNA, tRNA, mRNA. Gene Expression, information from a Gene is used in the synthesis of functional gene products. Molecular Levels Level one:1-DNA, 2-TranscriptionLevel Two - 1-RNA, 2-Translation, 3-RNACommon transcription factor motifs- Zinc finger - Helix-loop-helix (HLH) - Leucine zipper (LZ) - HMG box (high mobility group ) - Shared feature - Structurally stable framework - Specific DNA recognizing sequences are correctly positioned, Repression of Transcription Cells also possess negative regulatory elementsMechanisms: - Binding to promoter elements. - Blocking assembly of the preinitiation complex. - Inhibiting binding or functioning of transcriptional activators. - Modifying DNA and its interaction with nucleosomes. Some transcription factors activate some genes and repress others.
Autor: Rada Mohammed, Nebras
EAN: 9786205499887
Sprache: Englisch Deutsch
Seitenzahl: 104
Produktart: kartoniert, broschiert
Verlag: LAP Lambert Academic Publishing
Untertitel: Gene Regulation in Eukaryotic cell. DE
Schlagworte: Gene Expression gene regulation enhancer and silincer gene repression
Größe: 150 × 220