CD14 in the Inflammatory Response
The initial chapters in this volume describe the structure and ligand interactions of this important receptor molecule which is involved both in inflammation and in some aspects of apoptosis. The very recent results which illuminate the probable signal transduction pathways are also described. Overactivation of the inflammatory response can lead to systemic inflammation and septic shock. Attempts to intervene clinically in this system have been disappointing, and the reasons for these failures are discussed in the context of the expression of TNF which is upregulated by CD14. A discussion of new data on the clinical course of shock and the currently emerging therapeutic strategies rounds off the book.
| EAN: | 9783805569170 |
|---|---|
| Sprache: | Englisch |
| Seitenzahl: | 182 |
| Produktart: | Gebunden |
| Herausgeber: | Jack, R. S. Platts-Mills, T. A. E. |
| Verlag: | Karger |
| Schlagworte: | Lipopolysaccharide Fourteen |
| Größe: | 245 |
| Gewicht: | 526 g |
