The solution to the food problem in the Russian Federation depends primarily on the level of development of grain production, which largely determines the economic stability and food security of the country. Currently, winter wheat is the main grain crop in Rostov region, where it occupies more than 1.5 million hectares and accounts for 15...20% of Russia's winter wheat crop area. In order to get a high yield of crops, it is necessary to create the necessary conditions for growth and development of plants, to provide them with all the factors of life. The idea of optimizing mineral nutrition becomes particularly important nowadays, when there is a disparity between the prices of energy and agricultural products and the high cost of industrial fertilizers. The purpose of this work is to study the effect of fertilizers on mineral nutrition of winter wheat in the conditions of the Lower Don.pThe solution to the food problem in the Russian Federation depends primarily on the level of development of grain production, which largely determines the economic stability and food security of the country. Currently, winter wheat is the main grain crop in Rostov region, where it occupies more than 1.5 million hectares and accounts for 15...20% of Russia's winter wheat crop area. In order to get a high yield of crops, it is necessary to create the necessary conditions for growth and development of plants, to provide them with all the factors of life. The idea of optimizing mineral nutrition becomes particularly important nowadays, when there is a disparity between the prices of energy and agricultural products and the high cost of industrial fertilizers. The purpose of this work is to study the effect of fertilizers on mineral nutrition of winter wheat in the conditions of the Lower Don./p