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The Genetics and Development of Scoliosis

Our understanding of the genetic and developmental mechanisms underlying scoliosis is rapidly evolving, this timely second edition of The Genetics and Development of Scoliosis is to provide researchers, clinicians, and students with the most current views in this field. This volume brings together leaders in understanding congenital and idiopathic scoliosis to present the current state of research, and to compare the genetic etiology of these conditions, in order to identify potential shared developmental mechanisms. This book will summarize the recent advances in studies of spinal development and how disruptions during embryogenesis in embryonic segmentation can lead to congenital vertebral defects. In addition, recent reports of genetic loci predisposing patients to develop juvenile and adolescent idiopathic scoliosis will be presented, and key clinical features are reviewed. Finally, there will be discussion of how genetic heterogeneity and gene-environment interactions may contribute to congenital scoliosis and isolated vertebral malformations.
EAN: 9783319901480
Auflage: 002
Sprache: Englisch
Seitenzahl: 212
Produktart: Gebunden
Herausgeber: Dunwoodie, Sally L. Kusumi, Kenro
Verlag: Springer International Publishing Springer International Publishing AG
Veröffentlichungsdatum: 22.06.2018
Schlagworte: Biologie / Entwicklungsbiologie Entwicklungsbiologie Forschung (medizinisch, psychologisch) Genetik / Humangenetik Humangenetik Innere Medizin Medizin / Innere Medizin Heilkunde Humanmedizin Medizin Orthopädie Mensch / Physiologie Physiologie
Größe: 18 × 160 × 241
Gewicht: 489 g

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