Replicative Cessation & DNA Damage in Human Fibroblast under Stress
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Produktnummer:
9783846553268
Aging can be viewed partly as a degenerative process dictated by free radical reactions. Human diploid fibroblasts (HDFs) lose the capacity to proliferate and enter a state termed replicative senescence after a finite number of population doublings in vitro. Presenescent human fibroblasts, when treated with a sub-lethal dose of H2O2, enter long term growth arrest resembling replicative senescence. H2O2 induced growth arrest; p53 protein expression and the effect of vitamin C as an antioxidant were determined in this study.
| Autor: | Khalil, Sahar Hammouda, Gehad Hosny, Somaya |
|---|---|
| EAN: | 9783846553268 |
| Sprache: | Englisch |
| Seitenzahl: | 204 |
| Produktart: | kartoniert, broschiert |
| Verlag: | LAP Lambert Academic Publishing |
| Untertitel: | A study to investigate the replicative cessation, morphology and DNA damage in human fibroblasts under stress conditions |
| Schlagworte: | Vitamin C / Ascorbinsäure und and |
