Optimization in Drug Discovery
237,00 €*
Sofort verfügbar, Lieferzeit: 1-3 Tage
Produktnummer:
9781627037419
Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in vitro assays including formulation, plasma binding, absorption and permeability, cytochrome P450 (CYP) and UDP-glucuronosyltransferases (UGT) metabolism, CYP inhibition and induction, drug transporters, drug-drug interactions via assessment of reactive metabolites, genotoxicity, and chemical and photo-mutagenicity assays. Written for the Methods in Pharmacology and Toxicology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Expert authors have developed and utilized these in vitro assays to achieve ¿drug-like¿ characteristics in addition to efficacy properties and good safety profiles of drug candidates. Comprehensive and up-to-date, Optimization in Drug Discovery: In Vitro Methods, Second Edition aims to guide researchers down the difficult path to successful drug discovery and development.
| EAN: | 9781627037419 |
|---|---|
| Auflage: | 002 |
| Sprache: | Englisch |
| Seitenzahl: | 616 |
| Produktart: | Gebunden |
| Herausgeber: | Yan, Zhengyin Caldwell, Gary W. |
| Verlag: | Humana Press Humana Press Inc. |
| Veröffentlichungsdatum: | 09.11.2013 |
| Untertitel: | In Vitro Methods |
| Schlagworte: | Droge Sucht / Drogensucht Diagnose (medizinisch, psychiatrisch) / Labordiagnostik (medizinisch) Labordiagnostik (medizinisch) |
| Größe: | 37 × 183 × 260 |
| Gewicht: | 1339 g |
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